Technical problems in lung allotransplantation. Causes of pulmonary venous outflow obstruction

Gary H. Stevens, Decio M. Rangel, Yozo Yakeishi, Eric W. Fonkalsrud

UCLA School of Medicine.
United States

Archives of Surgery
Arch Surg 1969; 99: 506-512
DOI: 10.1001/archsurg.1969.01340160086020

Abstract
Experience in this laboratory with approximately 100 canine and primate lung allotransplantation operations over the past 18 months has made clear the fact that technical problems are the cause of a large number of graft failures.
In our series of 80 canine lung allotransplants which have been examined postmortem, more than 50% of failures appeared to be due to complete or partial obstruction to venous outflow from the graft. At least three distinct types of venous obstruction were encountered. The type of obstruction appears to be related to the duration of the posttransplant period, and may be characterized as acute, intermediate, and chronic venous outflow obstruction.

Category
Stenosis or Obstruction of Pulmonary Veins Following Heart or Lung Transplantation

Year of Publication: 1969

Age Focus: Pediatric or Adult

Article Type: Animal Models of Disease and Therapy

Article Access: Free PDF File or Full Text Article Available Through PubMed or DOI: No