Kuan-Chi Lai, Julie A. Brothers, Jason Z. Stoller
Children’s Hospital of Philadelphia.
United States
Cardiology in the Young
Cardiol Young 2019; 29: 541-543
DOI: 10.1017/S1047951119000167
Abstract
We report a case of severe hypertriglyceridemia associated with an everolimus drug-eluting stent in an infant with pulmonary vein stenosis. We review from current literature the mechanisms by which everolimus may cause dyslipidaemia, pharmacokinetics of everolimus in drug-eluting stents, and treatments of hypertriglyceridemia. This case demonstrates the need to closely monitor serum triglyceride levels after everolimus drug-eluting stent placement in infants.
Category
Stenosis or Obstruction of Normal Pulmonary Venous Connections
Patient Factors Influencing the Onset, Severity or Outcome of Disease
Catheter-mediated Interventions: Efficacy or Lack of Efficacy
Catheter-mediated Interventions: Adverse Effects or Lack of Adverse Effects
Medical Therapy to Prevent Recurrence of Disease after an Intervention. Efficacy or Lack of Efficacy
Medical Therapy. Adverse Effects or Lack of Adverse Effects
Medical Therapy. Pharmacokinetics or Pharmacology
Year of Publication: 2019
Age Focus: Pediatric
Article Type: Case Reports or Retrospective Observations in Small Groups of Patients (≤10 patients)
Article Access: Free PDF File or Full Text Article Available Through PubMed or DOI: No