Article Type: Animal Models of Disease and Therapy

A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms

Jin Shentu, Wenxuan Dai, Chang Chen, Jiawei Huang, Lijun Chen, Yi Yan, Han Zhang, Zhongqun Zhu, Guocheng Shi, Huiwen Chen Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026;DOI: 10.1016/j.jtcvs.2026.01.017 AbstractObjectives: Group 2 pulmonary hypertension (PH) remains a highly morbid disease, yet no specific […]

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Responses of systemic and pulmonary veins to the presence of an intravascular stent in a swine model

Martin Hosking, Mary Redmond, Lila Allen, Lother Broecker, Marilyn Keaney, Julie Lebeau, Virginia Walley Children’s Hospital of Eastern Ontario.Canada Catheterization and Cardiovascular DiagnosisCatheter Cardiovasc Diagn 1995; 36: 90-96DOI: 10.1002/ccd.1810360123 AbstractThe outcome of stent implantation for children with pulmonary venous obstruction has been characterized by late reocclusion associated with a marked vessel neointimal proliferation. The purpose of

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Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model

Debao Li, Yingying Xiao, Peisen Ruan, Zunmin Wan, Yuqing Hu, Sijuan Sun, Zheng Wang, Sixie Zheng, Yi Yan, Hao Chen, Hao Zhang, Chun Shen, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center. Women and Children’s Hospital of

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Bronchospirometric studies of pulmonary function after unilateral ligation of the pulmonary vein or the pulmonary artery

J. Gerald Mudd, William F. Kistner, C. Rollins Hanlon, Donald R. Burke St. Louis University.United States American Review of Respiratory DiseaseAm Rev Respir Dis 1965; 92: 589-596DOI: Not Available AbstractAbstract Not Available CategoryStenosis or Obstruction of Pulmonary Veins: Other CategoriesLength of Life Associated with Pulmonary Venous ObstructionDiagnostic Testing. Invasive Year of Publication: 1965 Age Focus:

Bronchospirometric studies of pulmonary function after unilateral ligation of the pulmonary vein or the pulmonary artery Read More »

The Influence of Congestion upon Tuberculosis in the Lung of the Dog

Olan R. Hyndman, Harry Landt, Dwight Mathes State University of Iowa.United States Annals of SurgeryAnn Surg 1940; 111: 564-576DOI: 10.1097/00000658-194004000-00006 AbstractAbstract Not Available CategoryStenosis or Obstruction of Pulmonary Veins: Other CategoriesLength of Life Associated with Pulmonary Venous Obstruction Year of Publication: 1940 Age Focus: None Article Type: Animal Models of Disease and Therapy Article Access: Free

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A neonatal rat model of pulmonary vein stenosis

Debao Li, Lisheng Qiu, Haifa Hong, Hao Chen, Peibin Zhao, Yingying Xiao, Hao Zhang, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University. Second Affiliated Hospital and Yuying Children’s Hospital and Wenzhou Medical University. China Cell and BioscienceCell Biosci 2023; 13:DOI: 10.1186/s13578-023-01058-8 AbstractObjectives: Pulmonary vein stenosis (PVS), one of the most challenging clinical

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Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis

Richard W. B. van Duin, Kelly Stam, André Uitterdijk, Beatrijs Bartelds, A. H. Jan Danser, Irwin K. M. Reiss, Dirk J. Duncker, Daphne Merkus Erasmus MC Rotterdam. Sophia Children’s Hospital. University Hospital, LMU Munich.Netherlands and Germany Journal of Clinical MedicineJ Clin Med 2019; 8DOI: 10.3390/jcm8081204 AbstractPulmonary hypertension (PH) as a result of pulmonary vein stenosis (PVS)

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Pulmonary vein stenosis and the pathophysiology of “upstream” pulmonary veins

Hideyuki Kato, Yaqin Yana Fu, Jiaquan Zhu, Shabana Aafaqi, Otto Rahkonen, Cameron Slorach, Alexandra Traister, Chung Ho Leung, David Chiasson, Luc Mertens, Lee Benson, Richard D. Weisel, Boris Hinz, Jason T. Maynes, John G. Coles, Christopher A. Caldarone Hospital for Sick Children and University of Toronto. Toronto General Hospital.Canada Journal of Thoracic and Cardiovascular SurgeryJ

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Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis

Jiaquan Zhu, Haruki Ide, Yaqin Yana Fu, Anouk-Martine Teichert, Hideyuki Kato, Richard D. Weisel, Jason T. Maynes, John G. Coles, Christopher A. Caldarone The Hospital for Sick Children and University of Toronto. Toronto General Hospital.Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2014; 148: 2550-2557DOI: 10.1016/j.jtcvs.2014.07.050 AbstractObjectives: Pulmonary vein stenosis (PVS) is a relentless disease

Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis Read More »

Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo

Takeshi Furukawa, Masahiko Kishiro, Hideo Fukunaga, Masahiro Ohtsuki, Ken Takahashi, Katsumi Akimoto, Toshiaki Shimizu, Shiori Kawasaki, Toshio Kumasaka Juntendo University School of Medicine.Japan Pediatric CardiologyPediatr Cardiol 2010; 31: 773-779DOI: 10.1007/s00246-010-9695-8 AbstractThe outcome of stent implantation for pulmonary vein stenosis (PVS) in children remains poor. Several reports describe placing drug-eluting stents to treat PVS, but their effectiveness

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