Medical Therapy to Prevent or Reverse the Onset of Disease. Efficacy or Lack of Efficacy

Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center.China ChildrenChildren 2026; 13:DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation, and […]

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. Frank Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes

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Combination Chemotherapy in Severe Pulmonary Vein Stenosis-A Case Series

Gabriel Krivenko, Karen Iacono, David Nykanen, Robyn Keen, Robert Sutphin, Michael Farias University of Central Florida. Orlando Health Arnold Palmer Hospital for Children. Boston Children’s Hospital.United States ChildrenChildren 2023; 10: DOI: 10.3390/children10020364 AbstractPulmonary vein stenosis results from a proliferative process that leads to the progressive obstruction of venous return to the left atrium. It is often

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New Paradigms for Pulmonary Vein Stenosis Treatment: When Surgery and Transcatheter Therapy Aren’t Good Enough

Usama B. Kanaan, William T. Mahle Children’s Healthcare of Atlanta and Emory University School of Medicine.United States Journal of PediatricsJ Pediatr 2018; 198: 12-13DOI: 10.1016/j.jpeds.2018.01.082 AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous ConnectionsStenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous ConnectionsMultidisciplinary CareMedical Therapy to Prevent or Reverse the

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Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding

Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States Journal of the American College of Cardiology Basic Translational ScienceJACC Basic Transl Sci 2025; 10: DOI: 10.1016/j.jacbts.2025.04.010 AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous ConnectionsPulmonary Hypertension Associated with Stenosis or Atresia of Pulmonary VeinsPulmonary Venous PathologyMedical Therapy to Prevent or Reverse the

Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding Read More »

Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model

Debao Li, Yingying Xiao, Peisen Ruan, Zunmin Wan, Yuqing Hu, Sijuan Sun, Zheng Wang, Sixie Zheng, Yi Yan, Hao Chen, Hao Zhang, Chun Shen, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center. Women and Children’s Hospital of

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Targeted Rapamycin Delivery via Magnetic Nanoparticles to Address Stenosis in a 3D Bioprinted in Vitro Model of Pulmonary Veins

Liqun Ning, Stefano Zanella, Martin M. Tomov, Medhi Salar Amoli, Linqi Jin, Bouen Hwang, Maher Saadeh, Huang Chen, Sunder Neelakantan, Lakshmi Prasad Dasi, Reza Avazmohammadi, Morteza Mahmooudi, Holly D. Bauser-Heaton, Vahid Serpooshan Emory University School of Medicine, Children’s Healthcare of Atlanta and Georgia Institute of Technology. Cleveland State University. Texas A&M University. Michigan State University.United

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In Search of the Holy Grail for Pediatric Pulmonary Vein Stenosis

Lourdes R. Prieto Nicklaus Children’s Hospital.United States Journal of the American College of CardiologyJ Am Coll Cardiol 2021; 77: 2819-2821DOI: 10.1016/j.jacc.2021.04.029 AbstractAbstract Not Available CategoryMedical Therapy to Prevent or Reverse the Onset of Disease. Efficacy or Lack of EfficacyMedical Therapy to Prevent Progression of Disease. Efficacy or Lack of EfficacyMedical Therapy to Prevent Recurrence of Disease

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Commentary: Targeting neointimal lesions in pulmonary vein stenosis: Fact or fiction?

Rachel D. Vanderlaan Hospital for Sick Children.Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2020; 160: 794-795DOI: 10.1016/j.jtcvs.2020.02.021 AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous ConnectionsStenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous ConnectionsMedical Therapy to Prevent or Reverse the Onset of Disease. Efficacy or Lack

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Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair

Edward C. Kirkpatrick, Michael E. Mitchell, MD, William G. Thilly, Joseph Cava, Aoy Tomita-Mitchell, Elena V. Gostjeva Children’s Hospital of Wisconsin and Medical College of Wisconsin. Massachusetts Institute of Technology. United States Global Pediatric HealthGlob Pediatr Health 2020;DOI: 10.1177/2333794X20958924 AbstractAbstract Not Available CategoryStenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous ConnectionsMedical Therapy to Prevent or Reverse the Onset of Disease. Efficacy or Lack

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