Medical Therapy to Prevent Progression of Disease. Efficacy or Lack of Efficacy

Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair

Edward C. Kirkpatrick, Michael E. Mitchell, MD, William G. Thilly, Joseph Cava, Aoy Tomita-Mitchell, Elena V. Gostjeva Children’s Hospital of Wisconsin and Medical College of Wisconsin. Massachusetts Institute of Technology. United States Global Pediatric HealthGlob Pediatr Health 2020;DOI: 10.1177/2333794X20958924 AbstractAbstract Not Available CategoryStenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous ConnectionsMedical Therapy to Prevent or Reverse the Onset of Disease. Efficacy or Lack […]

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A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children

Maliha Rehman, Kathy J. Jenkins, Amy L. Juraszek, Jean A. Connor, Kimberlee Gauvreau, Muhammad Muneeb, Laureen M. Sena, Steven D. Colan, Terry Saia, Mark W. Kieran Children’s Hospital, Boston.United States Congenital Heart DiseaseCongenit Heart Dis 2011; 6: 608-623DOI: 10.1111/j.1747-0803.2011.00574.x AbstractObjective: To determine the safety and efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of

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Intraluminal Pulmonary Vein Stenosis in Children: A “New” Lesion

Viviane G. Nasr, Ryan Callahan, Zachary Wichner, Kirsten C. Odegard, James A. DiNardo Boston Children’s Hospital.United States Anesthesia and AnalgesiaAnesth Analges 2019; 129: 27-40DOI: 10.1213/ANE.0000000000003924 AbstractPulmonary vein stenosis (PVS) is a rare disorder that leads to progressive narrowing of the extrapulmonary veins. PVS has been reported in both children and adults and in its worse iteration

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Systemic Sirolimus Therapy for Infants and Children With Pulmonary Vein Stenosis

Jay D. Patel, Michael Briones, Mansi Mandhani, Shannon Jones, Divya Suthar, Rosemary Gray, Joelle Pettus, Courtney McCraken, Amanda Thomas, Christopher J. Petit Emory University and Children’s Healthcare of AtlantaUnited States Journal of the American College of CardiologyJ Am Coll Cardiol 2021; 77: 2807-2818DOI: 10.1016/j.jacc.2021.04.013 AbstractBackground: Anatomic interventions for pulmonary vein stenosis (PVS) in infants and children have

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Management of Complex Pulmonary Vein Stenosis at Altitude Combining Comprehensive Percutaneous Interventional Treatment with Sirolimus, Pulmonary Hypertension Medications and Intraluminal Imaging with Optical Coherence Tomography

Michael J. Shorofsky, Gareth J. Morgan, Ernesto Mejia, Salvador A. Rodriguez, Megan Greene, Paige Sheaks, Dunbar Ivy, Jenny E. Zablah University of Colorado and Children’s Hospital Colorado.United States Pediatric CardiologyPediatr Cardiol 2023; Online ahead of printDOI: 10.1007/s00246-023-03102-3 AbstractBackground: Pulmonary vein stenosis (PVS) is a growing problem for the pediatric congenital heart population. Sirolimus has previously been shown

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Pulmonary vein stenosis: Treatment and challenges

Rachel D. Vanderlaan, Jonathan Rome, Russel Hirsch, Dunbar Ivy, Christopher A. CaldaroneHospital for Sick Children. Children’s Hospital of Philadelphia. Cincinnati Children’s Hospital. Children’s Hospital Colorado. Texas Children’s Hospital and Baylor College of Medicine.Canada and United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2021; 161: 2169-2176DOI: 10.1016/j.jtcvs.2020.05.117 AbstractNo Abstract CategoryStenosis or Obstruction of Normal

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The many faces and outcomes of pulmonary vein stenosis in early childhood

Tilman Humpl, Jeffrey Fineman, Athar M. Qureshi University Children’s Hospital Berne. University of California, San Francisco. Texas Children’s Hospital and Baylor College of Medicine.Switzerland and United States Pediatric PulmonologyPediatr Pulmonol 2021; 56: 649-655DOI: 10.1002/ppul.24848 AbstractPulmonary vein stenosis is a rare and poorly understood condition causing obstruction of the large pulmonary veins and of blood flow from

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Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Kimberlee Gauvreau, Audrey C. Marshall, Laureen M. Sena, Christopher W. Baird, Christina M. Ireland, Kerry McEnaney, Elsa C. Bjornlund, Juliana T. Mendonca, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8DOI: 10.3390/children8030210 AbstractThe purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis

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Aspiration Is Associated with Poor Treatment Response in Pediatric Pulmonary Vein Stenosis

Maria Niccum, Ryan Callahan, Kimberlee Gauvreau, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8DOI: 10.3390/children8090783 AbstractIntraluminal pulmonary vein stenosis is a disease with significant morbidity and mortality, though recent progress has been made using multimodal therapy with antiproliferative agents. The aim of this study was to evaluate the association between

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Adjunct Targeted Biologic Inhibition Agents to Treat Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Mark W. Kieran, Christopher W. Baird, Steven D. Colan, Kimberlee Gauvreau, Chistina M. Ireland, Audrey Marshall, Laureen M. Sena, Sara O. Vargas, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School. Floating Hospital for Children at Tufts Medical Center. UMass Memorial Medical Center.United States Journal of PediatricsJ Pediatr 2018; 198: 29-35DOI: 10.1016/j.jpeds.2018.01.029 AbstractObjective: To

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