Pulmonary Venous Pathology

Losartan attenuates upstream vasculopathy in a modified piglet model of pulmonary vein stenosis: contribution of the Hippo pathway

Wenhui Zeng, Siming Liu, Zhen Xu, Fangbao Ding, Ju Mei, Jiaquan Zhu Xinhua Hospital, Shanghai Jiaotong University School of Medicine.China Annals of Translational MedicineAnn Transl Med 2022; DOI: 10.21037/atm-22-2621 AbstractBackground: Diffuse pulmonary vein stenosis (PVS) is an intractable congenital heart disease for which the underlying mechanism remains unclear. In this study, we investigated the effect of losartan […]

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Swine model of chronic postcapillary pulmonary hypertension with right ventricular remodeling: long-term characterization by cardiac catheterization, magnetic resonance, and pathology

Daniel Pereda, Ana Garcia-Alvarez, Damián Sánchez-Quintana, Mario Nuño, Leticia Fernández-Friera, Rodrigo Fernández-Jiménez, José Manuel García Ruíz, Elena Sandoval, Jaume Aguero, Manuel Castellá. Roger J. Hajjar, Valentín Fuster, Borja Ibáñez Centro Nacional de Investigaciones Cardiovasculares Carlos III.Spain Journal of Cardiovascular Translational ResearchJ Cardiovasc Transl Res 2014; 7: 494-506DOI: 10.1007/s12265-014-9564-6 AbstractPulmonary hypertension (PH) is prevalent and carries high

Swine model of chronic postcapillary pulmonary hypertension with right ventricular remodeling: long-term characterization by cardiac catheterization, magnetic resonance, and pathology Read More »

Dynamic behavior and lineage plasticity of the pulmonary venous endothelium

Joanna Wong, Gan Zhao, Stephanie Adams-Tzivelekidis, Hongbo Wen, Prashant Chandrasekaran, Sylvia N. Michki, Maria E. Gentile, Madeline Singh, Sara Kass-Gergi, Meryl Mendoza, Nicolas P. Holcomb, Xinyuan Li, Alan T. Tang, Nicholas M. Negretti, Jennifer M. S. Sucre, David B. Frank, Andrew E. Vaughan University of Pennsylvania and Children’s Hospital of Philadelphia. Vanderbilt University Medical Center.

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Abnormal Pericyte Recruitment as a Cause for Pulmonary Hypertension in Adams–Oliver Syndrome

Millan S. Patel, Glenn P. Taylor, Simi Bharya, Nouriya Al-Sanna’a, Ian Adatia, David Chitayat, M.E. Suzanne Lewis, Derek G. Human Hospital for Sick Children and University of Toronto. Children’s and Women’s Health Center of British Columbia and University of British Columbia. Canada American Journal of Medical Genetics Am J Med Genet 2004; 129A: 294-299DOI: 10.1002/ajmg.a.30221 AbstractAdams-Oliver

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A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms

Jin Shentu, Wenxuan Dai, Chang Chen, Jiawei Huang, Lijun Chen, Yi Yan, Han Zhang, Zhongqun Zhu, Guocheng Shi, Huiwen Chen Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026;DOI: 10.1016/j.jtcvs.2026.01.017 AbstractObjectives: Group 2 pulmonary hypertension (PH) remains a highly morbid disease, yet no specific

A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms Read More »

Responses of systemic and pulmonary veins to the presence of an intravascular stent in a swine model

Martin Hosking, Mary Redmond, Lila Allen, Lother Broecker, Marilyn Keaney, Julie Lebeau, Virginia Walley Children’s Hospital of Eastern Ontario.Canada Catheterization and Cardiovascular DiagnosisCatheter Cardiovasc Diagn 1995; 36: 90-96DOI: 10.1002/ccd.1810360123 AbstractThe outcome of stent implantation for children with pulmonary venous obstruction has been characterized by late reocclusion associated with a marked vessel neointimal proliferation. The purpose of

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Congenital anomalies of the pulmonary veins

Saroja Bharati, Maurice Lev National Institutes of Health, National Heart and Lung InstituteUnited States Cardiovascular ClinicsCardiovasc Clin 1973; 5: 23-41DOI: Not Available AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous Connections Absence or Atresia of Normal Pulmonary Venous ConnectionsPulmonary Venous Pathology Year of Publication: 1973 Age Focus: Pediatric Article Type: Case Reports or

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Insights into the molecular mechanism of pulmonary vein stenosis in pediatric patients with congenital heart disease

Alyssa B. Kalustian, Pengfei Ji, Lalita Wadhwa, Christopher A. Caldarone, Manish Bansal, Athar M. Qureshi, Jeffrey S. Heinle, Ravi K. Birla Texas Children’s Hospital and Baylor College of Medicine. United States Journal of Thoracic and Cardiovascular Surgery OpenJTCVS Open 2025; 26: 166-181DOI: 10.1016/j.xjon.2025.04.012 AbstractObjective: Pediatric pulmonary vein stenosis (PVS) is associated with substantial morbidity and mortality for

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Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding

Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States Journal of the American College of Cardiology Basic Translational ScienceJACC Basic Transl Sci 2025; 10: DOI: 10.1016/j.jacbts.2025.04.010 AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous ConnectionsPulmonary Hypertension Associated with Stenosis or Atresia of Pulmonary VeinsPulmonary Venous PathologyMedical Therapy to Prevent or Reverse the

Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding Read More »

Congenital unilateral pulmonary venous atresia with pulmonary veno-occlusive disease in contralateral lung: an unusual association

Savitri Shrivastava, James H . Moller, Jesse E . Edwards University of Minnesota.United States Pediatric CardiologyPediatr Cardiol 1986; 7: 213-219DOI: 10.1007/BF02093183 AbstractA patient presenting with the rare association of congenital unilateral pulmonary venous atresia in one lung and pulmonary veno-occlusive disease in the other is described. The patient first presented at the age of 3 1/2

Congenital unilateral pulmonary venous atresia with pulmonary veno-occlusive disease in contralateral lung: an unusual association Read More »