Extreme dyspnea from unilateral pulmonary venous obstruction. Demonstration of a vagal mechanism and relief by right vagotomy

Scott F. Davies, Kenneth R. McQuaid, Conrad Iber, Charles McArthur, Michael Path, David S. Beebe, Hovald K. Helseth

University of Minnesota
United States

American Review of Respiratory Disease
Am Rev Respir Dis 1987; 136: 184-188
DOI: 10.1164/ajrccm/136.1.184

Abstract
A 43-yr-old woman developed severe exertional dyspnea after an unsuccessful attempt to correct a total right anomalous pulmonary venous connection. A clotted anastomosis resulted in unilateral pulmonary venous obstruction. Investigation excluded airway disease, left ventricular failure, and severe pulmonary hypertension as the cause of dyspnea. Exercise studies demonstrated a markedly abnormal ventilatory pattern consistent with excess vagal stimuli to the respiratory center. Temporary and then permanent vagal interruption markedly altered the respiratory pattern and improved her functional status from New York Heart Association Class III to Class I, confirming that vagal afferents were the cause of the dyspnea.

Category
Stenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous Connections
Symptoms and Quality of Life Associated with Pulmonary Venous Obstruction
Diagnostic Testing. Noninvasive

Year of Publication: 1987

Age Focus: Adult

Article Type: Case Reports or Retrospective Observations in Small Groups of Patients (≤10 patients)

Article Access: Free PDF File or Full Text Article Available Through PubMed or DOI: No