Tailoring stents to fit the anatomy of unique vascular stenoses in congenital heart disease

Patrick M. Sullivan, Aimee Liou, Cheryl Takao, Henri Justino, Christopher J. Petit, Jorge D. Salazar, Frank F. Ing

Children’s Hospital Los Angeles and University of Southern California Keck School of Medicine. Texas Children’s Hospital and Baylor College of Medicine. Children’s Healthcare of Atlanta and Emory University School of Medicine. Children’s Hospital Boston, Harvard Medical School
United States

Catheterization and Cardiovascular Interventions
Catheter Cardiovasc Interv 2017; 90: 963-971
DOI: 10.1002/ccd.27234

Abstract
Background: Unique and small anatomical features often preclude the use of available vascular stents in pediatric patients with congenital heart disease (CHD).
Objectives: To report our experience and outcomes tailoring stents to fit unique anatomy, particularly in small children and infants with CHD.
Methods: Stent tailoring techniques included trimming, folding, and flaring. Patients receiving a tailored stent November 2002 to February 2015 were included in a retrospective analysis.
Results: Forty-one tailored stents were implanted in 30 patients with median age and weight of 0.8 years (6 days to 17 years) and 8.1 kg (2.9-47.9 kg). Thirty stents were placed intraoperatively and 11 percutaneously. Sites included branch pulmonary arteries (BPA; n = 32), pulmonary veins (n = 6), SVC (n = 1), and the ventricular septum (n = 2). Twenty-three (56%) stents were trimmed with or without folding to avoid jailing of side branches, 16 (39%) stents were folded or flared with or without trimming to avoid excessive proximal protrusion, and two (5%) stents were folded back at both ends for implantation in ventricular septal defects. Final stent lengths were 6-15 mm. Minimal vessel diameters increased from 2.8 ± 1.4 mm to 6.7 ± 2.6 mm (P < 0.001). Complications included two intraoperative BPA tears, three pinhole balloon leaks, two intraoperative stent dislodgements, one transient heart block, and one lung reperfusion injury. Follow-up catheterization included 36 re-dilations and implantation of four additional stents over a median of 4.1 years. In-stent restenosis was the indication in 25 (69.4%) re-interventions.
Conclusion: Tailored stents can be safely implanted to fit unique anatomy in small patients. Re-interventions can effectively treat restenosis and accommodate ongoing vessel growth.

Category
Catheter-mediated Interventions: Efficacy or Lack of Efficacy
Catheter-mediated Interventions: Adverse Effects or Lack of Adverse Effects

Year of Publication: 2017

Age Focus: Pediatric

Article Type: Case Reports or Retrospective Observations in Small Groups of Patients (≤10 patients)

Article Access: Free PDF File or Full Text Article Available Through PubMed or DOI: No