Daijo Takajo, Paul J. Critser, Amr Matoq, Sarosh P. Batlivala, Shabana Shahanavaz, Russel Hirsch
Cincinnati Children’s Hospital Medical Center. University of Cincinnati College of Medicine.
United States
Pediatric Cardiology
Pediatr Cardiol 2025;
DOI: 10.1007/s00246-025-03955-w
Abstract
Pulmonary vein stenosis (PVS) in pediatric patients is associated with significant morbidity and requires repeated transcatheter interventions to maintain pulmonary vein patency. While these procedures can improve clinical outcomes, they come with inherent risks, and data on safety and post-procedural outcomes are limited. This single-center, retrospective study included pediatric patients who underwent transcatheter interventions for PVS between 2015 and 2024. Data were collected on patient demographics, procedural details, post-procedure disposition, adverse events (AEs), and hospital length of stay. Statistical analysis was performed to identify predictors of AEs. A total of 224 catheterization procedures were performed on 67 children with PVS. The overall AE rate was 11%, with the most common events including puncture site bleeding (5 cases), followed by pulse loss (4 cases), pulmonary hemorrhage (3 cases), stent embolization (3 cases), cerebrovascular accident (2 cases), contained vascular tear of pulmonary veins (2 cases), heart block (2 cases), supraventricular tachycardia (SVT, 2 cases), intra-abdominal hemorrhage associated with transhepatic access (1 case), and ST-segment changes (1 case). Despite these risks, most patients, particularly those treated on an outpatient basis, experienced short hospital stays. Operator experience and multidisciplinary care were critical in optimizing safety and outcomes. No statistically significant predictors of AEs were identified. Percutaneous interventions for PVS can be performed safely with strict adherence to standardized protocols, allowing for a controlled rate of complications despite increasing case volumes. While serious AEs such as cerebrovascular events and pulmonary hemorrhage remain a concern, targeted strategies may contribute to improved safety outcomes.
Category
Stenosis or Obstruction of Normal Pulmonary Venous Connections
Stenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous Connections
Catheter-mediated Interventions: Efficacy or Lack of Efficacy
Catheter-mediated Interventions: Adverse Effects or Lack of Adverse Effects
Year of Publication: 2025
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No