Article Type: Mechanical and Computational Models of Disease

An Integrated Lumped Parameter Model and Computational Fluid Dynamics Framework for Predicting Hemodynamic Parameters in Pulmonary Vein Stenosis

Alessia Di Nardo, David A. Romero, Rachel D. Vanderlaan, Cristina H. Amon University of Toronto and Hospital for Sick Children.Canada Comprehensive PhysiologyCompr Physiol 2026; 16: DOI: 10.1002/cph4.70185 AbstractPediatric pulmonary vein stenosis (PVS) is a progressive vascular disease associated with poor long-term outcomes. A growing body of evidence supports a relationship between the mechanisms of PVS pathogenesis […]

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Computational Predictive Modeling of Surgical Outcomes in Total Anomalous Pulmonary Venous Connection: Assessing the Impact of Pulmonary Venous Confluence Size on Preoperative Planning

Jie Jin, Zhuo Shi, Qiang Gao, Jing Yu, Irina Jin, Jiawei Liang, Xiangming Fan Children’s Hospital, Zhejiang University School of Medicine. Technical University of Moldova. China and Moldova Journal of Cardiovascular Translational ResearchJ Cardiovasc Transl Res 2025; 19: DOI: 10.1007/s12265-025-10725-9 AbstractTo develop a predictive model for optimal anastomosis sizing in TAPVC surgery, focusing on the role

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Balloon Dilation Technique Influences Stent Shortening and Intentional Stent Fracture During Overexpansion of Drug-Eluting Stents: A Bench-Testing Study

Mudit Gupta, Ella B. Leeth, Yuval Barak-Corren, Ari J. Gartenberg, Elizabeth Silvestro, Michael L. O’Byrne, Ryan Callahan Children’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Akron Children’s Hospital and Northeast Ohio Medical University.United States Catheterization and Cardiovascular InterventionsCatheter Cardiovasc Interv 2025;DOI: 10.1002/ccd.31428 AbstractBackground and aims: Drug-eluting stents (DES) are not designed for overexpansion

Balloon Dilation Technique Influences Stent Shortening and Intentional Stent Fracture During Overexpansion of Drug-Eluting Stents: A Bench-Testing Study Read More »

Patient-specific 3D in vitro modeling and fluid dynamic analysis of primary pulmonary vein stenosis

Christian Devlin, Martin L. Tomov, Huang Chen, Sindhu Nama, Siraj Ali, Sunder Neelakantan, Reza Avazmohammadi, Lakshmi Prasad Dasi, Holly D. Bauser-Heaton, Vahid Serpooshan Emory University School of Medicine and Georgia Institute of Technology. Texas A&M University. Children’s Healthcare of Atlanta.United States Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2024; 11:DOI: 10.3389/fcvm.2024.1432784 AbstractIntroduction: Primary pulmonary vein stenosis (PVS) is

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Targeted Rapamycin Delivery via Magnetic Nanoparticles to Address Stenosis in a 3D Bioprinted in Vitro Model of Pulmonary Veins

Liqun Ning, Stefano Zanella, Martin M. Tomov, Medhi Salar Amoli, Linqi Jin, Bouen Hwang, Maher Saadeh, Huang Chen, Sunder Neelakantan, Lakshmi Prasad Dasi, Reza Avazmohammadi, Morteza Mahmooudi, Holly D. Bauser-Heaton, Vahid Serpooshan Emory University School of Medicine, Children’s Healthcare of Atlanta and Georgia Institute of Technology. Cleveland State University. Texas A&M University. Michigan State University.United

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The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis: Evidence from Two Case Studies

Peter E. Hammer, Kerry McEnaney, Ryan Callahan, Christopher W. Baird, David M. Hoganson, Kathy J. Jenkins Boston Children’s Hospital.United States ChildrenChildren 2021; 8:DOI: 10.3390/children8090729 AbstractPulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants or children. It is often progressive and

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