Article Type: Computer and Mathematical Models of Disease and Therapy

A Computational Framework for Quantifying Hemodynamic Burden in Pediatric Pulmonary Vein Stenosis

Manish Bansal, Dan Lior, Avishek Mukherjee, Jeffrey S. Heinle, Athar M. Qureshi, Charles Puelz, Ravi K. Birla Texas Children’s Hospital and Baylor College of Medicine. University of Houston.United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026;DOI: 10.1016/j.jtcvs.2026.09.007 AbstractBackground: Pulmonary vein stenosis (PVS) is a rare but devastating pediatric disorder characterized by progressive

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An Integrated Lumped Parameter Model and Computational Fluid Dynamics Framework for Predicting Hemodynamic Parameters in Pulmonary Vein Stenosis

Alessia Di Nardo, David A. Romero, Rachel D. Vanderlaan, Cristina H. Amon University of Toronto and Hospital for Sick Children.Canada Comprehensive PhysiologyCompr Physiol 2026; 16: DOI: 10.1002/cph4.70185 AbstractPediatric pulmonary vein stenosis (PVS) is a progressive vascular disease associated with poor long-term outcomes. A growing body of evidence supports a relationship between the mechanisms of PVS pathogenesis

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Computational Predictive Modeling of Surgical Outcomes in Total Anomalous Pulmonary Venous Connection: Assessing the Impact of Pulmonary Venous Confluence Size on Preoperative Planning

Jie Jin, Zhuo Shi, Qiang Gao, Jing Yu, Irina Jin, Jiawei Liang, Xiangming Fan Children’s Hospital, Zhejiang University School of Medicine. Technical University of Moldova. China and Moldova Journal of Cardiovascular Translational ResearchJ Cardiovasc Transl Res 2025; 19: DOI: 10.1007/s12265-025-10725-9 AbstractTo develop a predictive model for optimal anastomosis sizing in TAPVC surgery, focusing on the role

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The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis: Evidence from Two Case Studies

Peter E. Hammer, Kerry McEnaney, Ryan Callahan, Christopher W. Baird, David M. Hoganson, Kathy J. Jenkins Boston Children’s Hospital.United States ChildrenChildren 2021; 8:DOI: 10.3390/children8090729 AbstractPulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants or children. It is often progressive and

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