Jie Jin, Zhuo Shi, Qiang Gao, Jing Yu, Irina Jin, Jiawei Liang, Xiangming Fan
Children’s Hospital, Zhejiang University School of Medicine. Technical University of Moldova.
China and Moldova
Journal of Cardiovascular Translational Research
J Cardiovasc Transl Res 2025; 19:
DOI: 10.1007/s12265-025-10725-9
Abstract
To develop a predictive model for optimal anastomosis sizing in TAPVC surgery, focusing on the role of pulmonary venous confluence (PVC) size. A patient-specific fluid-structure interaction (FSI) model simulated blood flow through various anastomosis sizes. Key variables included body weight, anastomosis length, and PVC size. The model’s predictions were validated against postoperative echocardiographic measurements from nine TAPVC cases. A strong positive correlation was found between flow velocity and the ratio of body weight to anastomosis length and PVC circumference. Including PVC size significantly improved predictive accuracy. No significant difference was observed between predicted and measured velocities. PVC size is a critical factor for planning TAPVC surgery. Incorporating it into computational models enhances the prediction of flow dynamics and supports personalized surgical decision-making.
Category
Stenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous Connections
Diagnostic Testing. Noninvasive
Year of Publication: 2026
Age Focus: Pediatric
Article Type: Mechanical and Computational Models of Disease
Article Access: Free PDF File or Full Text Article Available Through PubMed or DOI: Yes