Medical Therapy to Prevent Recurrence of Disease after an Intervention. Efficacy or Lack of Efficacy

Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation

Stasa Krasic, Antony Hermuzi, Ivan Dizdarevic, Vesna Topic, Nevena Djorovic, Mihail Basa, Vladislav Vukomanovic Mother and Child Health Institute of Serbia and University of Belgrade. Freeman Hospital and Newcastle upon Tyne Hospitals NHS Foundation Trust.Serbia and United Kingdom Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13:DOI: 10.3389/fcvm.2026.1783773 AbstractObjective: In patients who have undergone surgical repair of TAPVC […]

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Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center.China ChildrenChildren 2026; 13:DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation, and

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. Frank Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes

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Catheter and echocardiographic-focused management of primary pulmonary vein stenosis in premature infants: a single center 5-year experience

Keira Nassetta Conor P. O’Halloran, Emily Hoyt, Matthew Cornicelli, Nicolas Porta, Jeremy Fox, Alan W. Nugent, Paul Tannous, Amanda Hauck Ann and Robert H. Lurie Children’s Hospital of Chicago.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02611-2 AbstractBackground/objectives: We describe the outcomes of pulmonary vein stenosis treatment in a cohort of premature infants using an assertive percutaneous

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Severe hypertriglyceridemia associated with everolimus drug-eluting stent placement in an infant

Kuan-Chi Lai, Julie A. Brothers, Jason Z. Stoller Children’s Hospital of Philadelphia.United States Cardiology in the YoungCardiol Young 2019; 29: 541-543DOI: 10.1017/S1047951119000167 AbstractWe report a case of severe hypertriglyceridemia associated with an everolimus drug-eluting stent in an infant with pulmonary vein stenosis. We review from current literature the mechanisms by which everolimus may cause dyslipidaemia, pharmacokinetics

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New Paradigms for Pulmonary Vein Stenosis Treatment: When Surgery and Transcatheter Therapy Aren’t Good Enough

Usama B. Kanaan, William T. Mahle Children’s Healthcare of Atlanta and Emory University School of Medicine.United States Journal of PediatricsJ Pediatr 2018; 198: 12-13DOI: 10.1016/j.jpeds.2018.01.082 AbstractAbstract Not Available CategoryStenosis or Obstruction of Normal Pulmonary Venous ConnectionsStenosis or Obstruction of Pulmonary Veins Following Surgical Repair of Anomalous Pulmonary Venous ConnectionsMultidisciplinary CareMedical Therapy to Prevent or Reverse the

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Management of Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Brian H. Morray, Russel Hirsch, Christopher J. Petit Boston Children’s Hospital and Harvard Medical School. Seattle Children’s Hospital and University of Washington School of Medicine. Cincinnati Children’s Hospital and University of Cincinnati College of Medicine. Morgan Stanley Children’s Hospital, NewYork-Presbyterian Hospital and Columbia University Vagelos College of Physicians and Surgeons.United States Journal for

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Novel Use of Drug-Coated Balloon Angioplasty to Treat Pulmonary Vein Stenosis

Saloni Agrawal, Kali A. Hopkins, Ali N. Zaidi, Barry Love Mount Sinai Hospital. Mount Sinai Fuster Heart Hospital.United States Journal of the American College of Cardiology Case ReportsJACC Case Rep 2024; 29:DOI: 10.1016/j.jaccas.2024.102613 AbstractPulmonary vein stenosis is challenging to treat due to high rate of recurrence. Multiple interventions exist but are limited by high rates of

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Paclitaxel-coated drug-eluting balloon for pulmonary vein stenosis after repair of total anomalous pulmonary venous return with asplenia

Hiroshi Ono, Ryo Mafune, Taiyu Hayashi, Yasushi Misaki, Yukihiro Kaneko, Jumpei Saito, Miki Nagai, Hitoshi Kato National Medical Center for Child Health and Development.Japan Journal of Cardiology CasesJ Cardiol Cases 2020; 22: 107-109DOI: 10.1016/j.jccase.2020.05.008 AbstractWe used a paclitaxel-coated drug-eluting balloon (DEB) for pulmonary vein stenosis (PVS) after repair of total anomalous pulmonary venous return with asplenia.

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Paclitaxel drug-eluting stent placement for pulmonary vein stenosis as a bridge to heart-lung transplantation

Andreea Dragulescu, Olivier Ghez, Jacques Quilici, Alain Fraisse Centre Hospitalo-Universitaire La Timone.France Pediatric CardiologyPediatr Cardiol 2009; 30: 1169-1171DOI: 10.1007/s00246-009-9511-5 AbstractCongenital pulmonary vein stenosis (PVS) presents as an isolated lesion or in association with other congenital heart anomalies. The most extensive forms of the disease are uniformly fatal because neither surgical repair nor transcatheter therapy results in

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