Medical Therapy to Prevent Recurrence of Disease after an Intervention. Efficacy or Lack of Efficacy

Management of Complex Pulmonary Vein Stenosis at Altitude Combining Comprehensive Percutaneous Interventional Treatment with Sirolimus, Pulmonary Hypertension Medications and Intraluminal Imaging with Optical Coherence Tomography

Michael J. Shorofsky, Gareth J. Morgan, Ernesto Mejia, Salvador A. Rodriguez, Megan Greene, Paige Sheaks, Dunbar Ivy, Jenny E. Zablah University of Colorado and Children’s Hospital Colorado.United States Pediatric CardiologyPediatr Cardiol 2023; Online ahead of printDOI: 10.1007/s00246-023-03102-3 AbstractBackground: Pulmonary vein stenosis (PVS) is a growing problem for the pediatric congenital heart population. Sirolimus has previously been shown […]

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Pulmonary vein stenosis: Treatment and challenges

Rachel D. Vanderlaan, Jonathan Rome, Russel Hirsch, Dunbar Ivy, Christopher A. CaldaroneHospital for Sick Children. Children’s Hospital of Philadelphia. Cincinnati Children’s Hospital. Children’s Hospital Colorado. Texas Children’s Hospital and Baylor College of Medicine.Canada and United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2021; 161: 2169-2176DOI: 10.1016/j.jtcvs.2020.05.117 AbstractNo Abstract CategoryStenosis or Obstruction of Normal

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The many faces and outcomes of pulmonary vein stenosis in early childhood

Tilman Humpl, Jeffrey Fineman, Athar M. Qureshi University Children’s Hospital Berne. University of California, San Francisco. Texas Children’s Hospital and Baylor College of Medicine.Switzerland and United States Pediatric PulmonologyPediatr Pulmonol 2021; 56: 649-655DOI: 10.1002/ppul.24848 AbstractPulmonary vein stenosis is a rare and poorly understood condition causing obstruction of the large pulmonary veins and of blood flow from

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Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Kimberlee Gauvreau, Audrey C. Marshall, Laureen M. Sena, Christopher W. Baird, Christina M. Ireland, Kerry McEnaney, Elsa C. Bjornlund, Juliana T. Mendonca, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8DOI: 10.3390/children8030210 AbstractThe purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis

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Aspiration Is Associated with Poor Treatment Response in Pediatric Pulmonary Vein Stenosis

Maria Niccum, Ryan Callahan, Kimberlee Gauvreau, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8DOI: 10.3390/children8090783 AbstractIntraluminal pulmonary vein stenosis is a disease with significant morbidity and mortality, though recent progress has been made using multimodal therapy with antiproliferative agents. The aim of this study was to evaluate the association between

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Treatment of Congenital and Acquired Pulmonary Vein Stenosis

Patcharapong Suntharos, Lourdes R. Prieto Nicklaus Children’s Hospital.United States Current Cardiology ReportsCurr Cardiol Rep 2020; 22DOI: 10.1007/s11886-020-01395-x AbstractPurpose of review: Pulmonary vein stenosis (PVS) is a rare entity that until the last 2 decades was seen primarily in infants and children. Percutaneous and surgical interventions have limited success due to relentless restenosis, and mortality remains high. In

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Systemic Sirolimus to Prevent In-Stent Stenosis in Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Jesse J. Esch, Grace Wang, Christina M. Ireland, Kimberlee Gauvreau, Kathy J. Jenkins Boston Children’s Hospital and Harvard Medical School.United States Pediatric CardiologyPediatr Cardiol 2020; 41: 282-289DOI: 10.1007/s00246-019-02253-6 AbstractEvaluate the efficacy of systemic sirolimus (rapamycin) in preventing in-stent stenosis (ISS) in pediatric intraluminal pulmonary vein stenosis (PVS). Report the adverse events related to sirolimus

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Transcatheter Recanalization of Atretic Pulmonary Veins in Infants and Children

Jay D. Patel, Mansi Mandhani, Rosemary Gray, Joelle Pettus, Courtney E. McCracken, Amanda Thomas, Holly Bauser-Heaton, Dennis W. Kim, Christopher J. Petit Emory University and Children’s Healthcare of Atlanta. Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Morgan Stanley Children’s Hospital.United States Circulation Cardiovascular InterventionsCirc Cardiovasc Interv 2022; 15DOI: 10.1161/CIRCINTERVENTIONS.121.011351 AbstractBackground: Pulmonary vein stenosis is a progressive disease associated with a high rate of mortality in children. If left

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Clinical outcomes after the endovascular treatments of pulmonary vein stenosis in patients with congenital heart disease

Yoshihiko Kurita, Kenji Baba, Maiko Kondo, Takahiro Eitoku, Shingo Kasahara, Tatsuo Iwasaki, Shinichi Ohtsuki, Hirokazu Tsukahara Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.Japan Cardiology in the YoungCardiol Young 2019; 29: 1057-1065DOI: 10.1017/S1047951119001495 AbstractBackground: Pulmonary vein stenosis (PVS) is a condition with challenging treatment and leads to severe cardiac failure and pulmonary hypertension. Despite aggressive

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Comparison of drug eluting versus bare metal stents for pulmonary vein stenosis in childhood

Asra Khan, Athar M. Qureshi, Henri Justino Texas Children’s Hospital and Baylor College of Medicine.United States Catheterization and Cardiovascular InterventionsCatheter Cardiovasc Interv 2019; 94: 233-242DOI: 10.1002/ccd.28328 AbstractObjective: Comparison of outcomes using bare metal (BMS) and drug-eluting (DES) stents in pulmonary vein stenosis (PVS).Background: PVS is a serious condition with frequent restenosis after surgical and percutaneous interventions. After experiencing

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