Age Focus: Pediatric

Right Ventricular Function Improves With Pulmonary Vasodilator Treatment in Pediatric Patients With Pulmonary Hypertension and Multivessel Pulmonary Vein Stenosis in a Single Center Cohort

Catherine M. Avitabile, Kimberly Butler, Antara Mondal, David B. Frank, Yan Wang, Devon Ash, Laura Mercer‐Rosa, Michael L. O’Byrne, Ryan Callahan University of Pennsylvania, Perelman School of Medicine and Children’s Hospital of Philadelphia.United States Pulmonary CirculationPulm Circ 2026; 16:DOI: 10.1002/pul2.70346 AbstractPulmonary hypertension (PH) and right ventricular (RV) dysfunction increase mortality in multivessel pediatric pulmonary vein stenosis […]

Right Ventricular Function Improves With Pulmonary Vasodilator Treatment in Pediatric Patients With Pulmonary Hypertension and Multivessel Pulmonary Vein Stenosis in a Single Center Cohort Read More »

Pulmonary Venous Decompressing Collaterals: Angiographic Characteristics and Impact on Outcomes in Pediatric Pulmonary Vein Stenosis

Ashish Saini, Hui Huang, Andrew Jergel, Rosemary Gray, Dennis W. Kim, James Kuo Children’s Healthcare of Atlanta and Emory University School of Medicine.United States Pediatric CardiologyPediatr Cardiol 2026;DOI: 10.1007/s00246-026-04350-9 AbstractPediatric pulmonary vein stenosis (PVS) is a rare, progressive condition associated with significant morbidity and mortality. While pulmonary venous decompressing collaterals (PVDC) have been described, their clinical

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Utility of Follow-Up Surveillance Echocardiograms in Uncomplicated Surgical Closures of Perimembranous Ventricular Septal Defects: A Preliminary Analysis

Macala Maney, Carson Richardson, Isaac Kistler, Samantha Fichtner, Hannah Jacobs, Julie B. Aldrich, Clifford L. Cua Nationwide Children’s Hospital and Ohio State University Wexner Medical Center.United States Journal of Cardiovascular Development and Disease J Cardiovasc Dev Dis 2026; 13: DOI: 10.3390/jcdd13060281 AbstractBackground: Ventricular septal defects (VSD) are the most common form of congenital heart disease (CHD).

Utility of Follow-Up Surveillance Echocardiograms in Uncomplicated Surgical Closures of Perimembranous Ventricular Septal Defects: A Preliminary Analysis Read More »

Extracorporeal Membrane Oxygenation in Pediatric Pulmonary Hypertension: A Single-Center Cohort to Inform Decision-Making

Taylor M. Smith, Kathryn Restaino, Stuart Lipsitz, Jai Krishan Khurana, Mary P. Mullin, John N. Kheir, Katie M. Moynihan Boston Children’s Hospital, Brigham and Women’s Hospital and Harvard Medical School.United States American Society of Artificial Internal Organs JournalASAIO J 2026;DOI: 10.1097/MAT.0000000000002766 AbstractLimited data describe children with pulmonary hypertension (PH) supported on extracorporeal membrane oxygenation (ECMO). This

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Pulmonary vein stenosis after pediatric heart transplantation: incidence and risk factors

Hyun Soo Lee, Han Ki Park, Sang On Lee, Yu Rim Shin Severance Cardiovascular Hospital and Yonsei University College of Medicine.Republic of Korea Frontiers in SurgeryFront Surg 2026; 13: DOI: 10.3389/fsurg.2026.1820935 AbstractObjectives: Postoperative pulmonary vein stenosis (PVS) is an uncommon but potentially serious complication following pediatric heart transplantation. This study aimed to determine the prevalence of PVS

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Recurrent pulmonary vein stenosis potentially aggravated by posterior compression in a patient with asplenia

Takako Nishino, Makoto Ando Kanazawa Medical University.Japan Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04424-y AbstractPulmonary vein stenosis after repair of total anomalous pulmonary venous connection (TAPVC) is a life-threatening complication that frequently recurs, particularly in patients with asplenia. Although intrinsic mechanisms such as ostial narrowing and progressive neointimal proliferation are well recognized, extrinsic mechanical

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An Integrated Lumped Parameter Model and Computational Fluid Dynamics Framework for Predicting Hemodynamic Parameters in Pulmonary Vein Stenosis

Alessia Di Nardo, David A. Romero, Rachel D. Vanderlaan, Cristina H. Amon University of Toronto and Hospital for Sick Children.Canada Comprehensive PhysiologyCompr Physiol 2026; 16: DOI: 10.1002/cph4.70185 AbstractPediatric pulmonary vein stenosis (PVS) is a progressive vascular disease associated with poor long-term outcomes. A growing body of evidence supports a relationship between the mechanisms of PVS pathogenesis

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Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation

Stasa Krasic, Antony Hermuzi, Ivan Dizdarevic, Vesna Topic, Nevena Djorovic, Mihail Basa, Vladislav Vukomanovic Mother and Child Health Institute of Serbia and University of Belgrade. Freeman Hospital and Newcastle upon Tyne Hospitals NHS Foundation Trust.Serbia and United Kingdom Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13:DOI: 10.3389/fcvm.2026.1783773 AbstractObjective: In patients who have undergone surgical repair of TAPVC

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Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center.China ChildrenChildren 2026; 13:DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation, and

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Losartan attenuates upstream vasculopathy in a modified piglet model of pulmonary vein stenosis: contribution of the Hippo pathway

Wenhui Zeng, Siming Liu, Zhen Xu, Fangbao Ding, Ju Mei, Jiaquan Zhu Xinhua Hospital, Shanghai Jiaotong University School of Medicine.China Annals of Translational MedicineAnn Transl Med 2022; DOI: 10.21037/atm-22-2621 AbstractBackground: Diffuse pulmonary vein stenosis (PVS) is an intractable congenital heart disease for which the underlying mechanism remains unclear. In this study, we investigated the effect of losartan

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