Age Focus: Pediatric

Pulmonary vein stenosis after pediatric heart transplantation: incidence and risk factors

Hyun Soo Lee, Han Ki Park, Sang On Lee, Yu Rim Shin Severance Cardiovascular Hospital and Yonsei University College of Medicine.Republic of Korea Frontiers in SurgeryFront Surg 2026; 13: DOI: 10.3389/fsurg.2026.1820935 AbstractObjectives: Postoperative pulmonary vein stenosis (PVS) is an uncommon but potentially serious complication following pediatric heart transplantation. This study aimed to determine the prevalence of PVS […]

Pulmonary vein stenosis after pediatric heart transplantation: incidence and risk factors Read More »

Recurrent pulmonary vein stenosis potentially aggravated by posterior compression in a patient with asplenia

Takako Nishino, Makoto Ando Kanazawa Medical University.Japan Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04424-y AbstractPulmonary vein stenosis after repair of total anomalous pulmonary venous connection (TAPVC) is a life-threatening complication that frequently recurs, particularly in patients with asplenia. Although intrinsic mechanisms such as ostial narrowing and progressive neointimal proliferation are well recognized, extrinsic mechanical

Recurrent pulmonary vein stenosis potentially aggravated by posterior compression in a patient with asplenia Read More »

An Integrated Lumped Parameter Model and Computational Fluid Dynamics Framework for Predicting Hemodynamic Parameters in Pulmonary Vein Stenosis

Alessia Di Nardo, David A. Romero, Rachel D. Vanderlaan, Cristina H. Amon University of Toronto and Hospital for Sick Children.Canada Comprehensive PhysiologyCompr Physiol 2026; 16: DOI: 10.1002/cph4.70185 AbstractPediatric pulmonary vein stenosis (PVS) is a progressive vascular disease associated with poor long-term outcomes. A growing body of evidence supports a relationship between the mechanisms of PVS pathogenesis

An Integrated Lumped Parameter Model and Computational Fluid Dynamics Framework for Predicting Hemodynamic Parameters in Pulmonary Vein Stenosis Read More »

Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation

Stasa Krasic, Antony Hermuzi, Ivan Dizdarevic, Vesna Topic, Nevena Djorovic, Mihail Basa, Vladislav Vukomanovic Mother and Child Health Institute of Serbia and University of Belgrade. Freeman Hospital and Newcastle upon Tyne Hospitals NHS Foundation Trust.Serbia and United Kingdom Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13:DOI: 10.3389/fcvm.2026.1783773 AbstractObjective: In patients who have undergone surgical repair of TAPVC

Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation Read More »

Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center.China ChildrenChildren 2026; 13:DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation, and

Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models Read More »

Losartan attenuates upstream vasculopathy in a modified piglet model of pulmonary vein stenosis: contribution of the Hippo pathway

Wenhui Zeng, Siming Liu, Zhen Xu, Fangbao Ding, Ju Mei, Jiaquan Zhu Xinhua Hospital, Shanghai Jiaotong University School of Medicine.China Annals of Translational MedicineAnn Transl Med 2022; DOI: 10.21037/atm-22-2621 AbstractBackground: Diffuse pulmonary vein stenosis (PVS) is an intractable congenital heart disease for which the underlying mechanism remains unclear. In this study, we investigated the effect of losartan

Losartan attenuates upstream vasculopathy in a modified piglet model of pulmonary vein stenosis: contribution of the Hippo pathway Read More »

Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Heidi Van Christopher J. Petit, Oliver M. Barry Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital Morgan Stanley Children’s HospitalUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.007 AbstractPulmonary vein stenosis (PVS) is a rare and aggressive condition in infants and

Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent? Read More »

Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. Frank Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes

Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon Read More »

Pulmonary arterial hypertension caused by compression of the left lower pulmonary vein in children

Li Chen, Cheng Wang, Jiachen Li, Lizhi Lv, Yongtao Wu, Gang Li, Guofeng Xing, Xiaoyong Jing, Zhimin Liu, Qiang Wang Beijing Anzhen Hospital and Capital Medical University.  Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College.China Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026;DOI: 10.1186/s13019-026-04085-x AbstractObjectives To investigate, through

Pulmonary arterial hypertension caused by compression of the left lower pulmonary vein in children Read More »

Characteristics and outcomes of preterm infants with pulmonary vein stenosis in the contemporary era: a PHIS database analysis

Mohamed F. Elsisy, Fred Z. Lam, Mark M. Naguib, Mary E. Dees, James C. Gay, George T. Nicholson Monroe Carell Jr. Children’s Hospital at Vanderbilt. United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02703-z AbstractBackground: Pulmonary vein stenosis (PVS) is increasingly recognized in preterm infants, yet data regarding characteristics and outcomes remain limited.Methods: A review of hospitalizations from

Characteristics and outcomes of preterm infants with pulmonary vein stenosis in the contemporary era: a PHIS database analysis Read More »