Alterations in elastin and collagen related to the mechanism of progressive pulmonary venous obstruction in a piglet model. A hemodynamic, ultrastructural, and biochemical study
Jay I. LaBourene, John G. Coles, Dorothy J. Johnson, Arun Mehra, Fred W. Keeley, Marlene Rabinovitch Hospital for Sick Children.Canada Circulation ResearchCirc Res 1990; 66: 438-456DOI: 10.1161/01.res.66.2.438 AbstractWe created an animal model to understand better the pathogenesis and underlying mechanism of progressive central pulmonary venous (PV) obstruction, a condition not amenable to current therapy. Twenty piglets […]
