Article Type: Review

Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai Ye Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center.China ChildrenChildren 2026; 13:DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation, and […]

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Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Heidi Van Christopher J. Petit, Oliver M. Barry Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital Morgan Stanley Children’s HospitalUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.007 AbstractPulmonary vein stenosis (PVS) is a rare and aggressive condition in infants and

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. Frank Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes

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Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week

Trevor Simard, Dhruv Sarma, William R. Miranda, Charles Jain, Jason H. Anderson, Jeremy D. Collins, Abdallah El Sabbagh, Aravdeep Jhand, Tobias Peikert, Guy S. Reeder, Thomas M. Munger, Douglas L. Packer, David R. Holmes Mayo Clinic.United States Journal of the American College of CardiologyJ Am Coll Cardiol 2023; 81: 2361-2373DOI: 10.1016/j.jacc.2023.04.016 AbstractPulmonary vein stenosis (PVS) can

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Pediatric Pulmonary Vein Stenosis and Treatment

Joice Prodigios, Stephanie El Omeiri, Marcus Meneses, Bethelhem Belachew, Hansel J. Otero, David M. Biko, Jordan B. Rapp Children’s Hospital of Philadelphia and Perelman School of Medicine at The University of Pennsylvania.United States Seminars in RoentenologySemin Roentenol 2025; DOI: 10.1053/j.ro.2025.09.006 AbstractPulmonary vein stenosis (PVS) is an uncommon but often progressive condition in children, associated with high

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Application of sutureless technique in total anomalous pulmonary venous connection repair

Zhangwei Wang, Nan Ding, Hanlu Yi, Yaobin Zhu, Zhiqiang Li, Daole Yan, Xiaofeng Li, Song Bai Beijing Children’s Hospital, Capital Medical University and National Children’s Medical Center.China Journal of Cardiac SurgeryJ Card Surg 2022; 37: 3769-3775DOI: 10.1111/jocs.16843 AbstractThe sutureless technique was initially used for the treatment of postoperative pulmonary vein obstruction (PVO) in patients with total

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Pulmonary Vein Stenosis-Evolving Surgical Management of a Challenging Disease

Eric N. Feins, Ryan Callahan, Christopher W. Baird Boston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8: DOI: 10.3390/children8080631 AbstractPulmonary vein stenosis (PVS) is an extremely challenging clinical problem in congenital heart disease. It has traditionally required multimodal therapy given its complex underlying pathophysiology. As with other modalities, surgical therapy has undergone tremendous evolution

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Pulmonary Hypertension Associated with Bronchopulmonary Dysplasia: A Review

Nidhy Varghese, Danielle Rios Baylor College of Medicine and Texas Children’s Hospital.United States Pediatric Allergy Immunology and PulmonologyPediatr Allergy Immunol Pulmonol 2019; 32: 140-148DOI: 10.1089/ped.2018.0984 AbstractEarly pulmonary vascular disease (PVD) and established pulmonary hypertension (PH) are common associations of bronchopulmonary dysplasia (BPD). Diagnosis of PH is often made by echocardiography because of technical and logistic difficulties

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Surgical management of post-repair pulmonary vein stenosis

Edward J. Hickey, Christopher A. Caldarone Hospital for Sick Children.Canada Seminars in Thoracic and Gardiovascular Surgery PediatricsSemin Thorac Cardiovasc Surg Pediatr 2011; 14: 101-108DOI: 10.1053/j.pcsu.2011.01.007 AbstractObstructed pulmonary venous drainage – either in association with total anomalous pulmonary venous drainage, congenital stenosis, or post-repair stenosis – is associated with poor outcome. Post-repair stenosis typically involves fibrotic scar

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Lung transplantation and repair of complex congenital heart lesions in patients with pulmonary hypertension

Eric N. Mendeloff, Charles B. Huddleston Washington University School of Medicine.United States Seminars in Thoracic and Cardiovascular SurgerySemin Thorac Cardiovasc Surg 1998; 10: 144-151DOI: 10.1016/s1043-0679(98)70009-7 AbstractPulmonary vascular disease in conjunction with either a previously repaired or an unrepaired congenital heart defect is the third most common indication for lung transplantation in the pediatric age range. Because

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